abstract：:Evaluation of plant growth promoting bacteria and the associated metabolites under saline conditions can be a potential eco-friendly remediation and productivity enhancement strategy. Salt-tolerant Pseudomonas entomophila PE3 was isolated from saline soil and screened for plant growth promoting (PGP) traits. The isola...

journal_title：Microbiological research

authors： Fatima T,Arora NK

更新日期：2021-03-01 00:00:00

abstract：:Bladder cancer (BC) is one of the most common tumours of the urinary system and is also known as a highly malignant tumour. In addition to conventional diagnosis and treatment methods, recent research has focused on studying the molecular mechanisms related to BC, in the hope that new, less toxic and effective targete...

journal_title：Cellular signalling

authors： Wu G,Weng W,Xia P,Yan S,Zhong C,Xie L,Xie Y,Fan G

更新日期：2021-03-01 00:00:00

abstract：:β-lactamase inhibitors are potent synergistic drugs to deteriorate the multidrug-resistant bacteria. Here, we report the β-lactamase inhibitory ability of kalafungin isolated from a marine sponge derived Streptomyces sp. SBRK1. The IC50 value of the kalafungin was calculated as 225.37 ± 1.95 μM against β-lactamase. Th...

journal_title：Microbiological research

authors： Jabila Mary TR,Kannan RR,Muthamil Iniyan A,Carlton Ranjith WA,Nandhagopal S,Vishwakarma V,Prakash Vincent SG

更新日期：2021-03-01 00:00:00

abstract：:Polycystic ovarian syndrome (PCOS) presents as a constellation of clinical manifestations that can be varied among patients; however, the hormonal derangement associated with PCOS is uniformly characterized by excess androgens and abnormal insulin activity. The alteration in the normal hormonal milieu in these patient...

journal_title：Clinical obstetrics and gynecology

authors： Lindner PG

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Autoimmune hepatitis (AIH) is a chronic disease characterized by a lymphocyte infiltrate in the liver. For decades, nonspecific immunosuppression has been used to limit chronic liver inflammation. The high risk of relapse, the treatments side effects, and the significant number of refractory patients ...

journal_title：Current opinion in gastroenterology

authors： Cardon A,Conchon S,Renand A

更新日期：2021-03-01 00:00:00

abstract：:Cellulitis is a common clinical diagnosis in the outpatient and inpatient setting; studies have demonstrated a surprisingly high misdiagnosis rate: nearly one-third of cases are other conditions (ie, pseudocellulitis). This high rate of misdiagnosis is thought to contribute to nearly $515 million in avoidable health c...

journal_title：Infectious disease clinics of North America

authors： Garcia BM,Cruz-Diaz C,Agnihothri R,Shinkai K

更新日期：2021-03-01 00:00:00

abstract：:Renal fibrosis is characterized by chronic inflammation and excessive accumulation of extracellular matrix and progressively leads to functional insufficiency and even total loss of kidney function. In this study we investigated the anti-fibrotic potential of two highly selective and potent SK2 inhibitors, SLM6031434 ...

journal_title：Cellular signalling

authors： Schwalm S,Beyer S,Hafizi R,Trautmann S,Geisslinger G,Adams DR,Pyne S,Pyne N,Schaefer L,Huwiler A,Pfeilschifter J

更新日期：2021-03-01 00:00:00

abstract：:Sphingolipids and their synthetic enzymes have emerged as critical mediators in numerous diseases including inflammation, aging, and cancer. One enzyme in particular, sphingosine kinase (SK) and its product sphingosine-1-phosphate (S1P), has been extensively implicated in these processes. SK catalyzes the phosphorylat...

journal_title：Cellular signalling

authors： Velazquez FN,Hernandez-Corbacho M,Trayssac M,Stith JL,Bonica J,Jean B,Pulkoski-Gross MJ,Carroll BL,Salama MF,Hannun YA,Snider AJ

更新日期：2021-03-01 00:00:00

abstract：:This study identified adults' cooking practices patterns and tested their associations with children's consumption of ultra-processed foods. Cross-sectional study conducted with 551 adult-child pairs from São Paulo, Brazil. Children's food consumption was collected through dietary recalls. Adults' cooking practices we...

journal_title：Appetite

authors： Martins CA,Andrade GC,Oliveira MFB,Rauber F,Castro IRR,Couto MT,Levy RB

更新日期：2021-03-01 00:00:00

abstract：:Lithium is widely used in the treatment of bipolar disorder. Here we describe the syndrome of irreversible lithium-effectuated neurotoxicity in a patient within therapeutic doses and levels, which persisted after discontinuation of Lithium. A 50-year-old gentleman with Bipolar disorder presented with symptoms of Mania...

journal_title：International clinical psychopharmacology

authors： Jha A,Pai NM,Ganjekar S,Desai G,Chaturvedi SK

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND:Previous data show that lidocaine or magnesium has unique characteristics of stress inhibition and antiinflammation. OBJECTIVE:We aimed to observe the effects of lidocaine or magnesium on the quality of recovery (QoR) after laparoscopic cholecystectomy. DESIGN:Single-centre, prospective, randomised, double...

journal_title：European journal of anaesthesiology

authors： Lu J,Wang JF,Guo CL,Yin Q,Cheng W,Qian B

更新日期：2021-03-01 00:00:00

abstract：:The crosstalk between glial cells and neurons represents an exceptional feature for maintaining the normal function of the central nervous system (CNS). Increasing evidence has revealed the importance of glial progenitor cells in adult neurogenesis, reestablishment of cellular pools, neuroregeneration, and axonal (re)...

journal_title：Glia

authors： Martins-Macedo J,Lepore AC,Domingues HS,Salgado AJ,Gomes ED,Pinto L

更新日期：2021-03-01 00:00:00

abstract：:Cancer stem cells (CSC) are essential for tumorigenesis. The transcription factor Sox2 is overexpressed in brain gliomas, and is essential to maintain CSC. In mouse high-grade glioma pHGG cells in culture, Sox2 deletion causes cell proliferation arrest and inability to reform tumors after transplantation in vivo; in S...

journal_title：Glia

authors： Barone C,Buccarelli M,Alessandrini F,Pagin M,Rigoldi L,Sambruni I,Favaro R,Ottolenghi S,Pallini R,Ricci-Vitiani L,Malatesta P,Nicolis SK

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Field research indicates that lower intelligence may predispose trauma-exposed individuals towards the development of re-experiencing symptoms. However, this assumption requires further testing in controlled prospective studies. In the current analog study, we tested whether lower fluid intell...

journal_title：Journal of behavior therapy and experimental psychiatry

authors： Roxanne Sopp M,Streb M,Brueckner AH,Schäfer SK,Lass-Hennemann J,Mecklinger A,Michael T

更新日期：2021-03-01 00:00:00

abstract：OBJECTIVES:The early diagnosis and monitoring of Crohn's disease (CD) and orofacial granulomatosis (OFG) might be facilitated by assaying potential disease biomarkers in saliva. Markers of oxidative stress and inflammation were assayed in salivas from patients with CD, OFG and concurrent OFG and CD (OFG + CD). SUBJECT...

journal_title：Oral diseases

authors： Janšáková K,Escudier M,Tóthová Ľ,Proctor G

更新日期：2021-03-01 00:00:00

abstract：OBJECTIVE:To attempt defining differential radiographic diagnostic characteristics for osteonecrotic lesions using 2D as opposed to 3D images. MATERIALS AND METHODS:This was a cross-sectional study. Subjects presenting mandibular osteonecrotic lesions (osteomyelitis, osteoradionecrosis, and medication-related osteonec...

journal_title：Oral diseases

authors： Gaêta-Araujo H,Vanderhaeghen O,Vasconcelos KF,Coucke W,Coropciuc R,Politis C,Jacobs R

更新日期：2021-03-01 00:00:00

abstract：:Lead (Pb) is one of the most hazardous pollutants and toxic heavy metal in marine environment. The molecular mechanisms of Pb toxicity in aquatic organism are not well understood. In this study, hepatopancreas transcriptome of Litopenaeus vannamei (L. vannamei) was characterized by a comparison between control and Pb ...

journal_title：Biological trace element research

authors： Jiao L,Dai T,Jin M,Sun P,Zhou Q

更新日期：2021-03-01 00:00:00

abstract：:Nutritional profile of minerals and antioxidants in Indian spice extracts was evaluated in order to examine their efficacy in treating various diseases, disorders, and allergies in human health. Extracts of four medicinal plants such as Curcuma longa, Zingiber officinale, Piper nigrum, and Piper longum, regularly cons...

journal_title：Biological trace element research

authors： Swain S,Rautray TR

更新日期：2021-03-01 00:00:00

abstract：:The protective effects of caffeic acid on angiotensin-converting enzyme (ACE) and purinergic enzyme activities, as well as gluconeogenesis was investigated in iron-induced cardiotoxicity. Cardiotoxicity was induced in heart tissues harvested from healthy male SD rats by 0.1 mM FeSO4. Treatment was carried out by co-in...

journal_title：Biological trace element research

authors： Salau VF,Erukainure OL,Islam MS

更新日期：2021-03-01 00:00:00

abstract：:This study analysed 330 environmental substrates from three dairy farms for the occurrence, drug resistance and the genetic mutations of MTBC (Mycobacterium tuberculosis complex) in Eastern Cape, South Africa using PCR, while the Genotype MTBDRplus assay was used for drug susceptibility and genetic mutations analyses....

journal_title：International journal of environmental health research

authors： Ntloko A,Adefisoye MA,Green E

更新日期：2021-03-01 00:00:00

abstract：:This study aims to perform a bioactive analysis of five mushrooms collected in south of Brazil. The total phenol content of the extracts was equivalent to the antioxidant activity by ACAP assay. All extracts were able to inhibit the growth of Acinetobacter baumanni, and Auricularia auricula and Lactarius deliciosus ex...

journal_title：International journal of environmental health research

authors： Volcão LM,Halicki PB,Bilibio D,Ramos DF,Bernardi E,Da Silva Júnior FMR

更新日期：2021-03-01 00:00:00

abstract：:Lavender and immortelle essential oils (EOs) are widely used to treat a spectrum of human conditions. The aim of this study was to investigate cyto/genotoxic effects of lavender and immortelle EOs using plant cells (Allium cepa) and human lymphocytes, as well as their antimicrobial potential using nine strains of bact...

journal_title：Drug and chemical toxicology

authors： Mesic A,Mahmutović-Dizdarević I,Tahirović E,Durmišević I,Eminovic I,Jerković-Mujkić A,Bešta-Gajević R

更新日期：2021-03-01 00:00:00

abstract：:S-[3-carbamoylsulfanyl-2-(dimethylamino)propyl] carbamothioate (Cartap) (CAS number: 15263-52-2) is a synthetic insecticide of thiocarbamates group that is extensively used in field of agriculture for controlling of several pests like rice stem borer, leaf folder pests in paddy field and diamond back moth, aphids in c...

journal_title：Drug and chemical toxicology

authors： Sharma LP,Kadve MP,Lingaraju MC,Telang AG

更新日期：2021-03-01 00:00:00

abstract：PURPOSE:Phosphorus spectroscopy (31 P-MRS) is a proven method to probe cardiac energetics. Studies typically report the phosphocreatine (PCr) to adenosine triphosphate (ATP) ratio. We focus on another 31 P signal: inorganic phosphate (Pi), whose chemical shift allows computation of myocardial pH, with Pi/PCr providing ...

journal_title：Magnetic resonance in medicine

authors： Apps A,Valkovič L,Peterzan M,Lau JYC,Hundertmark M,Clarke W,Tunnicliffe EM,Ellis J,Tyler DJ,Neubauer S,Rider OJ,Rodgers CT,Schmid AI

更新日期：2021-03-01 00:00:00

abstract：PURPOSE:A MR thermometry (MRT) method with field monitoring is proposed to improve the measurement of small temperature variations induced in brain MRI exams. METHODS:MR thermometry experiments were performed at 7 Tesla with concurrent field monitoring and RF heating. Images were reconstructed with nominal k-space tra...

journal_title：Magnetic resonance in medicine

authors： Le Ster C,Mauconduit F,Mirkes C,Bottlaender M,Boumezbeur F,Djemai B,Vignaud A,Boulant N

更新日期：2021-03-01 00:00:00

abstract：:Acute asthma exacerbations are primarily due to airway inflammation and remain one of the most frequent reasons for childhood hospitalizations. Although systemic corticosteroids remain the mainstay of therapy because of their anti-inflammatory properties, not all inflammatory pathways are responsive to systemic cortic...

journal_title：Journal of clinical pharmacology

authors： Arnold DH,Van Driest SL,Reiss TF,King JC,Akers WS

更新日期：2021-03-01 00:00:00

abstract：:Glasdegib is approved for treating acute myeloid leukemia in elderly patients at 100 mg once daily in combination with low-dose cytarabine. Exposure-efficacy analysis showed that the survival benefit of glasdegib was not glasdegib exposure-dependent. The relationship between glasdegib exposure and adverse event (AE) c...

journal_title：Journal of clinical pharmacology

authors： Ruiz-Garcia A,Shaik N,Lin S,Jamieson C,Heuser M,Chan G

更新日期：2021-03-01 00:00:00

abstract：:Sterile inflammatory processes are essential for the maintenance of central nervous system homeostasis, but they also contribute to various neurological disorders, including neurotrauma, stroke, and demyelinating or neurodegenerative diseases. Immune mechanisms in the central nervous system and periphery are regulated...

journal_title：Neural regeneration research

authors： Klegeris A

更新日期：2021-03-01 00:00:00

abstract：:The baker's yeast Saccharomyces (S.) cerevisiae is a single-celled eukaryotic model organism widely used in research on life sciences. Being a unicellular organism, S. cerevisiae has some evident limitations in application to neuroscience. However, yeast prions are extensively studied and they are known to share some ...

journal_title：Neural regeneration research

authors： Ishikawa T

更新日期：2021-03-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate post-transcriptional gene expression and contribute to all aspects of cellular function. We previously reported that the activities of several mitochondria-enriched miRNAs regulating inflammation (i.e., miR-142-3p, miR-142-5p, and miR-146a) are altere...

journal_title：Neural regeneration research

authors： Wang WX,Prajapati P,Vekaria HJ,Spry M,Cloud AL,Sullivan PG,Springer JE

更新日期：2021-03-01 00:00:00

abstract：:Epidural electrical stimulation can restore limb motor function after spinal cord injury by reactivating the surviving neural circuits. In previous epidural electrical stimulation studies, single electrode sites and continuous tetanic stimulation have often been used. With this stimulation, the body is prone to declin...

journal_title：Neural regeneration research

authors： Wang S,Zhang LC,Fu HT,Deng JH,Xu GX,Li T,Ji XR,Tang PF

更新日期：2021-03-01 00:00:00

abstract：PURPOSE:Imaging of [2-13 C]lactate, a metabolic product of [2-13 C]pyruvate, is over considerable interest in hyperpolarized 13 C studies. However, artifact-free imaging of a J-coupled nuclear spin species can be challenging due to the peak-splitting induced by the spin-spin interactions. In this work, two new techniqu...

journal_title：Magnetic resonance in medicine

authors： Datta K,Spielman D

更新日期：2021-03-01 00:00:00

abstract：AIM:To investigate the impact of concussion on pupillary function in children by examining pupillometric parameters and assessing for differences in children reporting photosensitivity. METHODS:Retrospective chart review was performed of pediatric patients referred for visual symptoms after concussion from 2017 to 201...

journal_title：Journal of child neurology

authors： Hsu J,Stec M,Ranaivo HR,Srdanovic N,Kurup SP

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND:The National Drug Abuse Treatment Clinical Trials Network (CTN) multisite comparative-effectiveness study ("X:BOT") by Lee et al. (2018) found that, once initiated, extended-release naltrexone (XR-NTX) is as similarly safe and effective as sublingual buprenorphine-naloxone (BUP-NX) for the treatment of opioi...

journal_title：Journal of substance abuse treatment

authors： Gauthier P,Greco P,Meyers-Ohki S,Desai A,Rotrosen J

更新日期：2021-03-01 00:00:00

abstract：:Tocilizumab (TCZ), a humanized monoclonal antibody targeting the interleukin-6 receptor, holds the potential for treating coronavirus disease 2019 (COVID-19) patients, particularly those at high risk of cytokine storm syndrome. However, data regarding the clinical impact of treatment with TCZ in patients with COVID-19...

journal_title：Journal of clinical pharmacology

authors： Mo Y,Adarkwah O,Zeibeq J,Pinelis E,Orsini J,Gasperino J

更新日期：2021-03-01 00:00:00

abstract：:Decabromodiphenyl ethane (DBDPE) is a novel environmental pollutant that has attracted growing attention. Previous studies have indicated that DBDPE could induce vascular endothelial injury and cardiovascular damage, but the underlying mechanisms are not well understood. This study was designed to examine the mechanis...

journal_title：Chemosphere

authors： Zheng D,Shi Z,Yang M,Liang B,Zhou X,Jing L,Sun Z

更新日期：2021-03-01 00:00:00

abstract：:In this research, a novel iron based bimetallic nanoparticles (Fe-Ni) supported on activated carbon (AC) were synthesized and employed as an activator of persulfate in polycyclic aromatic hydrocarbons (PAHs) polluted sites remediation. AC-supported Fe-Ni activator was prepared according to two-step reduction method: t...

journal_title：Chemosphere

authors： Tian H,Chen C,Zhu T,Zhu B,Sun Y

更新日期：2021-03-01 00:00:00

abstract：:In organisms, activation of mitochondrial unfolded protein response (mt UPR) provides the protective strategy against toxicity of environmental exposures. The aim of this study was to determine the activation of intestinal mt UPR and the underlying mechanisms in nanopolystyrene (100 nm) exposed Caenorhabditis elegans....

journal_title：Chemosphere

authors： Liu H,Wang D

更新日期：2021-03-01 00:00:00

abstract：:Maximum utilization of the full solar spectrum has been considered as a holy grail in the field of photocatalysis and has emerged important in the recent years, as the world needs to move towards renewable energy sources and also to maintain environmental health. In the search for a sustainable solution, we have come ...

journal_title：Chemosphere

authors： Jain A,Kumar A,Kaur H,Krishnan V

更新日期：2021-03-01 00:00:00

abstract：:Landfills are a potential threat to human health and the environment, especially from the detrimental and toxic heavy metals. This study focuses on the assessment of heavy metals contamination in leachate and surface soils from different landfills in Malaysia. Maximum quality rating scale (QRS) values of As (787) and ...

journal_title：Chemosphere

authors： Hussein M,Yoneda K,Mohd-Zaki Z,Amir A,Othman N

更新日期：2021-03-01 00:00:00